Bruno Yu - MSFT
jankonijnenberg,
It seems that your project is not compiled in VB Express Edition. I guess you are programming in Visual Studio 2005 and your project need a packege from J#. In this situation, I suggest you to completely install your VS and download the SP1 for the IDE. Generally speaking, when you compile the project on the .NET Framework 2.0 successfully, the project will work fine.
When publishing, the .NET Framework provide the ClickOnce technology for your deployment. You can either publish the project by localhost and install them in the web browser, or publish on your local disk with an exist path then click the setup file to install.
I hope that your problem has been solved now. If you have any question, please reply me.